Virus as Populations: Composition, Complexity, Quasispecies, Dynamics, and Biological Implications
Original price was: $111.77.$65.75Current price is: $65.75.
9780128163313, Academic Press, Domingo, Esteban
Author: Domingo, Esteban
Brand: Academic Press
Edition: 2
ISBN: 9780128163313
Release Date: 01-11-2019
Package Dimensions: 9.3 x 7.5 x 1.1 inches
Languages: English
Binding: paperback
Number Of Pages: 426
Details: Virus as Composition, Complexity, Quasispecies, Dynamics, and Biological Implications, Second Edition, explains the fundamental concepts surrounding viruses as complex populations during replication in infected hosts. Fundamental phenomena in virus behavior, such as adaptation to changing environments, capacity to produce disease, and the probability to be transmitted or respond to treatment all depend on virus population numbers. Concepts such as quasispecies dynamics, mutations rates, viral fitness, the effect of bottleneck events, population numbers in virus transmission and disease emergence, and new antiviral strategies are included.
The book’s main concepts are framed by recent observations on general virus diversity derived from metagenomic studies and current views on the origin and role of viruses in the evolution of the biosphere. Features current views on key steps in the origin of life and origins of viruses Includes examples relating ancestral features of viruses with their current adaptive capacity Explains complex phenomena in an organized and coherent fashion that is easy to comprehend and enjoyable to read Considers quasispecies as a framework to understand virus adaptability and disease processes
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