Translational Models of Parkinson’s Disease and related Movement Disorders

Author: Mohamed MD PhD, Wael

Edition: 1

ISBN: 9780443161285

Release Date: 27-11-2024

Package Dimensions: 11.0 x 8.5 x 1.0 inches

Languages: English

Binding: Paperback

Number Of Pages: 386

Details: Translational Models of Parkinson’s Disease and Related Movement Disorders focuses on cutting-edge techniques for creating and validating current Parkinson’s Disease translational experimental models. Various characteristics of these models are examined, including the prion-like properties of -synuclein, mitochondrial functions connected to the PINK1-Parkin pathway/CHCHD2, the endolysosome pathway connected to LRRK2, VPS35, and ATP13A2 using cultured cells (including patient iPS cells). This book also highlights the future possibilities of introducing new models for Parkinson’s Disease and related movements disorders, underscoring current advancements, pre-clinical and clinical developments, and future scope related to numerous models. Highlights induction and validation of different available experimental models of Parkinson’s Disease Provides a comparative prospect of different experimental models of Parkinson’s Disease Discusses the advantages and disadvantages of each model, including associated limitations