Transketolases (Volume 722) (Methods in Enzymology, Volume 722)
Original price was: $287.56.$169.15Current price is: $169.15.
Transketolases (Volume 722) (Methods in Enzymology, Volume 722) | 9780443430510, Bastien, Doumèche
Original price was: $287.56.$169.15Current price is: $169.15.
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Author: Doumèche, Bastien
Edition: 1
ISBN: 9780443430510
Release Date: 05-12-2025
Languages: English
Binding: hardcover
Number Of Pages: 520
Details: Transketolase is an ubiquitous enzyme which has not yet finished revealing all its secrets. This Methods in Enzymology: Transketolases volume is devoted to the description of cutting-edge methods to its study in biochemistry. Several topics are addressed by world experts in their field.
The first part of this volume deals with transketolase at the cellular level. The latest scientific progress on human transketolase TKL1 in relation to certain diseases and to its inhibition are discussed including the involvement of this enzyme in new metabolic pathways or as a diagnostic biomarker.
The second part focuses on transketolase at the molecular level. The structural and mechanistic aspects linked to this enzyme are addressed using several approaches including molecular modelling and crystallography, for example. Finally, the experimental methodological approaches relating to the use of transketolase as a tool of choice in biocatalysis is presented. Cutting-edge methodologies to study Transketolase from cellular to molecular contexts Detailed protocols described by selected experts and easily applicable to other enzymes A compilation of the methods for studying transketolases in a single volume
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