Osteoimmunology: Interactions of the Immune and Skeletal Systems
Original price was: $151.73.$89.25Current price is: $89.25.
9780128005712, Academic Press, Joseph, Lorenzo
Author: Lorenzo, Joseph
Brand: Academic Press
Edition: 2
ISBN: 9780128005712
Release Date: 20-10-2015
Package Dimensions: 9.1 x 6.6 x 1.1 inches
Languages: English
Binding: hardcover
Format: Illustrated
Number Of Pages: 376
Details: Osteoimmunology: Interactions of the Immune and Skeletal Systems, Second Edition, explores the advancements that have been made in the field during the last 40 years, including valuable information on our understanding of the interactions between hematopoietic, immune, and bone cells, now known as the field of osteoimmunology.
This comprehensive work offers the most extensive summaries of research trends in the field and their translation into new therapeutics.
Early chapters deal with the development of osteoblasts, osteoclasts, hematopoietic stem cells, T and B-lymphocytes, and communications between these cellular elements, while later sections contain discussions of the signaling pathways by which RANKL influences osteoclast development and function. Subsequent chapters explore the effects that estrogen has on bone and the immune system, the development of pathologic conditions, and the growing research around osteoporosis, Paget’s disease, the genetics of bone disease, and bone cancer metastasis. Explains the intricate interaction between the immune system and bone Features detailed discussions of the key cellular and molecular mechanisms governing the homeostasis of the individual systems Facilitates greater understanding of osteoimmunologic networks, their environments, and how this understanding leads to better treatments for human diseases involving both systems
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