FROM GLOBULAR PROTEINS TO AMYLOIDS
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9780081029817, Elsevier, Irena, Roterman-Konieczna PhD
Original price was: $216.75.$127.50Current price is: $127.50.
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Author: Roterman-Konieczna PhD, Irena
Brand: Elsevier
Edition: First Edition
ISBN: 9780081029817
Release Date: 10-10-2019
Package Dimensions: 9.0 x 6.1 x 1.2 inches
Languages: English
Binding: Paperback
Number Of Pages: 278
Details: From Globular Proteins to Amyloids proposes a model and mechanism for explaining protein misfolding. Concepts presented are based on a model originally intended to show how proteins attain their native conformations. This model is quantitative in nature and founded upon arguments derived from information theory. It facilitates prediction and simulation of the amyloid fibrillation process, also identifying the progressive changes that occur in native proteins that lead to the emergence of amyloid aggregations. Introduces basic rules for protein folding, along with the conditions that result in misfolding Presents research that lies in treating the aqueous environment as a continuum rather than a set of individual water molecules (i.e. the classic representation) Provides practical applications for helping the prevention of amyloidosis and improving drug design
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