Fundamentals of Molecular Structural Biology

Author: Pal PhD, Subrata

Edition: 2

ISBN: 9780443339806

Release Date: 15-05-2026

Languages: English

Binding: paperback

Number Of Pages: 650

Details: Fundamentals of Molecular Structural Biology, Second Edition reviews the mathematical and physical foundations of molecular structural biology, covering the latest advancements in the field. The book begins with a historical perspective before exploring a range of topics including mathematical concepts, physical aspects of chemistry, chemical basis of biology, structural analysis and visualization, protein folding, transcription, RNA processing, cell signaling, and computational molecular biology. Additionally this new edition delves into AI fundamentals and applications, including AlphaFold and RoseTTAFold. In recent years AI has made a big impact upon molecular structural biology, and this book explores the latest developments in this area. This fully updated edition provides a detailed overview of the fundamental concepts across molecular structural biology and acts as an ideal guide for researchers and advanced students working in this area. Given the increasingly interdisciplinary nature of this subject, early career researchers and those shifting into an adjacent field often require a “fundamentals” book to get them up-to-speed on the foundations of a particular field. This book fills that niche. Explores AI contributions to the study of molecular structural biology, from fundamental concepts to applications Describes the latest techniques and approaches in the field, including cryo-electron tomography and nuclear magnetic resonance Provides a current and easily digestible resource on molecular structural biology, discussing both foundations and the latest advances Addresses critical issues surrounding macromolecular structures, such as structure-based drug discovery, single-particle analysis, computational molecular biology/molecular dynamic simulation, cell signaling and immune response, macromolecular assemblies, and systems biology Presents discussions that ultimately lead the reader toward a more detailed understanding of the basis and origin of disease