Protein Misfolding (Volume 118) (Advances in Protein Chemistry and Structural Biology, Volume 118)

Author: Donev, Rossen

Brand: Academic Press

Edition: 1

ISBN: 9780128177501

Release Date: 21-01-2020

Package Dimensions: 9.4 x 6.3 x 1.4 inches

Languages: English

Binding: hardcover

Number Of Pages: 450

Details: Protein Misfolding, Volume 118, covers the wide spectrum of diseases and disorders that are attributed to protein misfolding, including degenerative and neurodegenerative, cardiovascular, renal, glaucoma, cancer, cystic fibrosis, Gaucher’s disease, and many others. Specific chapters cover Mass spectrometric approaches for profiling protein folding and stability, Biomembranes, a key player in protein misfolding, how Genetic and environmental factors interact to disrupt proteostasis and trigger protein misfolding diseases, Formation of oligomers and large amorphous aggregates by intrinsically disordered proteins, Protein misfolding in ER stress with applications to cardiovascular and renal disease, and much more. Integrates methods for studying protein misfolding, factors that trigger this process and its role in a wide spectrum of diseases and disorders Contains timely chapters written by well-renowned authorities in their field Provides data that is well supported by a number of high quality illustrations, figures and tables, and targets a very wide audience of specialists, researchers and students