Sirtuins in Health and Disease (Volume 154) (Progress in Molecular Biology and Translational Science, Volume 154)
Original price was: $247.10.$145.35Current price is: $145.35.
9780128122617, Academic Press, Weiping, Zheng
Original price was: $247.10.$145.35Current price is: $145.35.
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Author: Zheng, Weiping
Brand: Academic Press
Edition: 1
ISBN: 9780128122617
Release Date: 10-02-2018
Package Dimensions: 9.5 x 6.5 x 0.8 inches
Languages: English
Binding: hardcover
Number Of Pages: 186
Details: Sirtuins in Health and Disease, Volume 154 presents the reactions catalyzed by sirtuins in terms of their unique coenzyme NAD+-dependent catalytic mechanisms, the ways to elucidate these mechanisms, and the design of the inhibitory compounds against the sirtuin-catalyzed reactions as potential therapeutic agents for human diseases. Sections cover the concepts and chemical tools in sirtuin research, SIRT4 and SIRT7, the regulatory effects of NAD metabolic pathways on sirtuin activity, sirtuins as modifiers of Huntington’s Disease (HD) pathology, parasite sirtuins as targets for novel chemotherapeutic agents, targeting sirtuins – substrate specificity and inhibitor design, and chemical probes in sirtuin research.
This book focuses on the outstanding issues in the sirtuin field and implications for future sirtuin research. Presents an excellent subject, excellent structural organization, and authoritative contributions from world-renowned scholars in the sirtuin field Provides the latest updates on sirtuins in health and disease
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