Nonclinical Assessment of Abuse Potential for New Pharmaceuticals
Original price was: $140.89.$82.88Current price is: $82.88.
9780124201729, Academic Press, Carrie, Markgraf MD PhD
Original price was: $140.89.$82.88Current price is: $82.88.
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Author: Markgraf MD PhD, Carrie
Brand: Academic Press
Edition: 1
ISBN: 9780124201729
Release Date: 21-08-2015
Package Dimensions: 9.8 x 7.8 x 0.9 inches
Languages: English
Binding: hardcover
Number Of Pages: 320
Details: Nonclinical Assessment of Abuse Potential for New Pharmaceuticals offers a complete reference on the current international regulatory guidelines and details best practice methodology for the three standard animal models used to evaluate abuse potential: physical dependence, self-administration and drug discrimination. This book also includes chapters on alternative models and examples of when you should use these alternatives. Case histories are provided at the end of the book to show how the data generated from the animal models play a pivitol role in the submission package for a new drug. By incorporating all of this information into one book, Nonclinical Assessment of Abuse Potential for New Pharmaceuticals is your single resource for everything you need to know to understand and implement the assessment of abuse liability. Provides a consolidated overview of the complex regulatory landscape Offers best practice methodology for conducting animal studies, including selection of doses and positive control agents that will help you improve your own abuse potential studies Includes real-life examples to illustrate how nonclinical data fit into the submission strategy
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